Tag: CYP3A4 drug interaction
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Azoles and Tacrolimus: How Antifungals Cause Dangerous Drug Spikes and Kidney Damage
Azoles like voriconazole and posaconazole can spike tacrolimus levels by 300% or more, leading to kidney damage in transplant patients. Learn how to prevent this dangerous interaction with dose adjustments, monitoring, and safer alternatives.
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Clarithromycin and Statins: How to Avoid Muscle Toxicity Interactions
Clarithromycin can dangerously increase statin levels in the blood, raising the risk of muscle damage and kidney failure. Learn which statins are safest, how to avoid the interaction, and why azithromycin is the better antibiotic choice.